Royal Air Force Typhoon FGR4s have conducted a mission with French aircraft in a joint strike on an subterranean weapons facility in Syrian territory employed by the IS group, according to the British defence ministry.
The facility, identified by surveillance, was assessed as containing munitions and bombs, the announcement noted, and was positioned in mountainous terrain just north of Palmyra in central Syria.
"Our fighter planes utilized Paveway IV guided bombs to hit a several access tunnels leading to the depot... preliminary assessments suggest the strike was effective," officials stated.
There was no indication of any civilian casualties in the attack late on Saturday and all the aircraft made a safe return, the ministry further stated.
The British jets were backed up by a Voyager refuelling tanker.
The Islamic State group - also known as ISIS - imposed extremist governance over large swathes of Iraq and Syria prior to its 2019 collapse.
"This operation demonstrates our UK leadership, and commitment to work closely with our allies, to eliminate any re-emergence of Daesh and their violent and radical beliefs in the area," UK Defence Secretary the minister said.
UK warplanes have conducted surveillance missions over Syrian airspace to "prevent any attempted resurgence" of Islamic State following its routing at the climactic battle in Baghuz in 2019, the authorities noted.
"I want to thank all the members of our armed forces involved in this operation for their skill and their valour," the Defence Secretary said. "They were among numerous British personnel deployed over the festive period. This operation, to eliminate militants who threaten our security, shows how our armed forces are ready to step up, continuously, ensuring Britain's security within its borders and influential overseas."
In December, the American forces conducted what it described as a "massive strike" against Islamic State objectives in the country, subsequent to an assault resulted in the deaths of two American soldiers and a local interpreter in the Palmyra area.
The U.N. reports Islamic State still maintains an estimated 5,000 to 7,000 combatants in Iraq and Syria.